2020-9-3 · Allergic rhinitis (AR) is a common chronic inflammatory disease of the upper respiratory tract. Di (2-ethylhexyl) phthalate (DEHP) is a widely used plasticizer and belongs to environmental
2018-4-16 · Di‐(2‐ethylhexyl) phthalate (DEHP) is an environmental endocrine disruptor widely used in China that is harmful to the male reproductive system. Many studies have shown that DEHP causes testicular toxicity through oxidative stress but the specific mechanism is unknown. Because the Notch pathway is a key mechanism for regulating cell growth
2021-7-13 · Bis (2-ethylhexyl) phthalate also known as di (2-ethylhexyl) phthalate or DEHP a branched-chain dioctyl ester of phthalic acid is the most important phthalate plasticizer used in Canada. In 1991 production of bis (2-ethylhexyl) phthalate in Canada totalled approximately 5 kilotonnes (kt) and an additional 5 kt were imported.
2 days ago · Health risks posed by use of Di-2-ethylhexyl phthalate (DEHP) in PVC medical devices a critical review. Am J Ind Med 39(1) 100-11. 41 National toxicology programm the US department of health and human services (11/2006) Center for the evaluation of risks to human reproduction NTP-CERHR Monograph on the Potential Human Reproductive and
2 days ago · DEHP is on the Proposition 65 list because it can cause cancer and birth defects or other reproductive harm. Exposure to DEHP may increase the risk of cancer and may also harm the male reproductive system. Exposure to DEHP during pregnancy may affect the development of the child. Proposition 65 requires businesses to determine if they must provide a warning about exposure to
2018-4-16 · Di-(2-ethylhexyl) phthalate (DEHP) is an environmental endocrine disruptor widely used in China that is harmful to the male reproductive system. Many studies have shown that DEHP causes testicular toxicity through oxidative stress but the specific mechanism is unknown.
2015-7-26 · The study objective was to determine if the healthy participants were exposed to diethyl phthalate (DEP) and di (2-ethylhexyl) phthalate (DEHP) and if this exposure could be linked to the development of metabolic syndrome. The study included 103 healthy volunteers of similar age with normal BMI values waist circumference total cholesterol HDL LDL and triglycerides.
2017-1-10 · Bis(2-ethylhexyl)phthalate (also BEHP di-2-ethyl hexyl phthalate DEHP or dioctyl phthalate DOP) is a phthalate a branched-chain viscosity.. Use. Due to its low cost DEHP is widely used as a lightsticks.. Environmental exposure. DEHP is slowly released into the air from finished Food and Drug Administration (FDA) therefore permits use of DEHP-containing packaging only for foods that
2016-10-7 · Di(2-ethylhexyl) phthalate (DEHP) is the most common plasticizer of polyvinyl chloride (PVC) products (Guo and Kannan 2011).Approximately 3–4 millions of tons of DEHP are produced each year worldwide and have been used in numerous consumer products commodities building materials and medical products (Heudorf et al. 2007).Since DEHP is not permanently bound to the PVC polymer in
2017-1-10 · Bis(2-ethylhexyl)phthalate (also BEHP di-2-ethyl hexyl phthalate DEHP or dioctyl phthalate DOP) is a phthalate a branched-chain viscosity.. Use. Due to its low cost DEHP is widely used as a lightsticks.. Environmental exposure. DEHP is slowly released into the air from finished Food and Drug Administration (FDA) therefore permits use of DEHP-containing packaging only for foods that
2013-11-27 · This toxicological profile on di-(2-ethylhexyl) phthalate (DEHP) describes its effects on freshwater and marine life humans and laboratory animals. Because of its prevalence in the environment and the high likelihood of exposures to humans and other species DEHP has been the subject of considerable toxicological research. Use and Exposure
2018-2-22 · Di-2-ethylhexyl phthalate (DEHP) is extensively used as a plasticizer in many products especially medical devices furniture materials cosmetics and personal care products. DEHP is noncovalently bound to plastics and therefore it will leach out of these products after repeated use heating and/or cleaning of the products.
2021-6-12 · Five of the most widely used phthalates are di- (2-ethylhexyl) phthalate (DEHP) dibutyl phthalate (DBP) di-isononyl phthalate (DINP) di-isodecyl phthalate (DIDP) and benzyl butyl phthalate (BBP). These phthalates have been assessed within an EU program on Risk Assessment for new and existing chemical substances.
2016-10-7 · Di(2-ethylhexyl) phthalate (DEHP) is the most common plasticizer of polyvinyl chloride (PVC) products (Guo and Kannan 2011).Approximately 3–4 millions of tons of DEHP are produced each year worldwide and have been used in numerous consumer products commodities building materials and medical products (Heudorf et al. 2007).Since DEHP is not permanently bound to the PVC polymer in
2019-1-18 · phthalates DEHP DBP DiBP and BBP as toxic to reproductive health for example. In ani-mal trials Di(2-propylheptyl) phthalate (DPHP) has a harmful effect on the pituitary gland (hypophysis) and on the vital endocrine hormone the thyroid. The pituitary gland controls important bodily functions and the hormonal system of the body.
2019-8-1 · As one of the most common PAEs di-2-ethylhexyl phthalate (DEHP) has been shown by toxicological studies to be an endocrine disruptor that may cause cancer in humans and is listed as a priority contaminant by the US Environmental Protection Agency (USEPA) (Martino-Andrade and Chahoud 2010 Gao et al. 2016a Chen et al. 2018).
2011-10-6 · Approximately 55 of ingested DEHP is absorbed. DEHP is poorly absorbed through the skin. There are no quantitative absorption data for the inhalation route. Following ingestion DEHP is rapidly broken down in the gut to mono(2-ethylhexyl)phthalate and 2-ethylhexanol. 3 DEHP is lipophilic and tends to accumulate in adipose tissues.
For example some of the PAEs e.g. Dibutyl phthalate (DBP) Di(2-Ethylhexyl) phthalate (DEHP) Butyl Benzyl phthalate (BBP) and Diethyl phthalate (DEP) have bioaccumulation potentials and are considered endocrine-disrupting chemicals and classified by many countries as "priority pollutants" (Lu et al. 2009).
2013-12-5 · Di-2-ethylhexyl phthalate (DEHP) is a reproductive and developmental toxicant and the developing male reproductive tract is most sensitive to DEHP exposures. Because DEHP is used in many consumer products and is a ubiquitous environmental contami-nant humans are exposed to DEHP at some level on a daily basis throughout life from conception
2018-6-6 · Di-2-ethylhexyl phthalate (DEHP) is a commonly used plasticizer that is harmful to human health. magnetic resonance spectroscopy from the edible fruit flesh of Benincasa hispida (wax gourd) of the plant family Curcurbitaceae. The DEHP content of seven wax gourd samples collected from southern and northern provinces in China was determined as (mean ± SD) 18.3 ± 0.43 2.64 ± 0.44 44.0 ± 0
Di (2-ethylhexyl) phthalate (DEHP) is found in many plastics. Exposure to DEHP is generally very low. Increased exposures may come from intravenous fluids delivered through plastic tubing and from ingesting contaminated foods or water. DEHP is not toxic at
2 days ago · DEHP is on the Proposition 65 list because it can cause cancer and birth defects or other reproductive harm. Exposure to DEHP may increase the risk of cancer and may also harm the male reproductive system. Exposure to DEHP during pregnancy may affect the development of the child. Proposition 65 requires businesses to determine if they must provide a warning about exposure to
2018-4-16 · Di‐(2‐ethylhexyl) phthalate (DEHP) is an environmental endocrine disruptor widely used in China that is harmful to the male reproductive system. Many studies have shown that DEHP causes testicular toxicity through oxidative stress but the specific mechanism is unknown. Because the Notch pathway is a key mechanism for regulating cell growth
Assay of vtg ERs and PPARs as endpoint for the rapid in vitro screening of the harmful effect of Di-(2-ethylhexyl)-phthalate (DEHP) and phthalic acid (PA) in zebrafish primary hepatocyte cultures. Maradonna F(1) Evangelisti M Gioacchini G Migliarini B Olivotto I Carnevali O.
Di(2-ethylhexyl) phthalate (DEHP) is a common indoor pollutant in the world which may cause lots of harmful effects in human including diabetes according to epidemiological studies. To explore the underlying role of DEHP in diabetes-like symptoms Balb/c mice were chose to be the experimental animals in this paper. They were separated as eight groups as follows (1) saline normal diet
2013-12-5 · Di-2-ethylhexyl phthalate (DEHP) is a reproductive and developmental toxicant and the developing male reproductive tract is most sensitive to DEHP exposures. Because DEHP is used in many consumer products and is a ubiquitous environmental contami-nant humans are exposed to DEHP at some level on a daily basis throughout life from conception
2004-9-1 · Di(2-ethylhexyl) phthalate (DEHP) is used to make polyvinyl chloride (PVC) plastic tubing soft and flexible. Animal data show that adverse effects of DEHP exposure may include reduced fertility reduced sperm production in males and ovarian dysfunction in females.
2018-10-24 · Reduction of Di-2 ethylhexyl Phthalate (DEHP) in Respiratory Therapy Products . exposure to harmful chemicals that are known to pose health risks. DEHP is used as a plasticizer to make tubing and other medical plastics more flexible and is known to leach from plastic during use and thereby enter the patient. Respiratory therapy
What is DEHP DEHP which is an abbreviation for di(2-ethylhexyl) phthalate is a manufactured chemical that is commonly added to plastics to make them flexible. Other names for this compound are dioctyl phthalate (DOP) and bis(2-ethylhexyl) phthalate (BEHP). (Note that di-n-octyl phthalate however is the name for a different chemical.)
2015-7-26 · Di-2-ethylhexyl phthalate (DEHP) and diethyl phthalate (DEP) are among the most commonly used harmful phthalates. Phthalates do not tend to bioaccumulate in the body as they have a very fast metabolism.
2019-8-1 · As one of the most common PAEs di-2-ethylhexyl phthalate (DEHP) has been shown by toxicological studies to be an endocrine disruptor that may cause cancer in humans and is listed as a priority contaminant by the US Environmental Protection Agency (USEPA) (Martino-Andrade and Chahoud 2010 Gao et al. 2016a Chen et al. 2018).
2015-7-26 · The study objective was to determine if the healthy participants were exposed to diethyl phthalate (DEP) and di (2-ethylhexyl) phthalate (DEHP) and if this exposure could be linked to the development of metabolic syndrome. The study included 103 healthy volunteers of similar age with normal BMI values waist circumference total cholesterol HDL LDL and triglycerides.
2019-1-18 · phthalates DEHP DBP DiBP and BBP as toxic to reproductive health for example. In ani-mal trials Di(2-propylheptyl) phthalate (DPHP) has a harmful effect on the pituitary gland (hypophysis) and on the vital endocrine hormone the thyroid. The pituitary gland controls important bodily functions and the hormonal system of the body.
2020-9-3 · Di(2-ethylhexyl) phthalate (DEHP) is a widely used plasticizer and belongs to environmental endocrine disruptors (EDCs). It can be entered the human body which is harmful to health. The relationship between DEHP and AR is still inconclusive. This study aims
2021-7-22 · The human population may be exposed to DEHP by swallowing it for example in food by breathing it in and to a much lesser extent by skin contact. Risks are assessed by dividing worst-case exposures to the exposures at which no harmful effects were observed in animal studies. This gives the margin of safety (MOS).
2003-5-15 · The efficiency of two lypolytic enzymes (fungal cutinase yeast esterase) in the degradation of di-(2-ethylhexyl)-phthalate (DEHP) was investigated. The DEHP-degradation rate of fungal cutinase was surprisingly high i.e. almost 70 of the initial DEHP (500 mg/l) was decomposed within 2.5 h and nearly 50 of the degraded DEHP disappeared within the initial 15 min.
2020-9-3 · Di(2-ethylhexyl) phthalate (DEHP) is a widely used plasticizer and belongs to environmental endocrine disruptors (EDCs). It can be entered the human body which is harmful to health. The relationship between DEHP and AR is still inconclusive. This study aims
2011-10-21 · DEHP which is an abbreviation for di(2-ethylhexyl) phthalate is a manufactured chemical that is commonly added to plastics to make them flexible. Other names for this compound are dioctyl phthalate (DOP) and bis(2-ethylhexyl) phthalate (BEHP). (Note that di-n-octyl phthalate however is the name for a different chemical.) Trade names used for DEHP include Platinol DOP Octoil Silicol 150 Bisoflex 81 and Eviplast 80. DEHP is a colorless liquid with almost no odor. It does not evaporate easily and little will be present in the air even near sources of production. It dissolves more easily in materials such as gasoline paint removers and oils than it does in water. It is present in many plastics especially vinyl materials which may contain up to 40 DEHP although lower levels are common. DEHP
2018-2-22 · Di-2-ethylhexyl phthalate (DEHP) is extensively used as a plasticizer in many products especially medical devices furniture materials cosmetics and personal care products. DEHP is noncovalently bound to plastics and therefore it will leach out of these products after repeated use heating and/or cleaning of the products.
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